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While GC-MS may have slightly lower sensitivity compared to LC-MS for certain acylcarnitines, its particularly useful for analyzing smaller or more volatile acylcarnitines in complex matrices

Therefore, we concluded that Sirt1 and Sirt3 prefer deacetylation to debutyrylation, whereas Sirt2, Sirt6, and Sirt7 have the opposite preferences

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317 , H674H684 (2019)